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As a prescription drug, it is used to treat acetaminophen poisoning (to protect the liver), but general claims of "liver protection" and detoxification are not well established

Establishment of K7M2-Luc orthotopic osteosarcoma mouse model and therapeutic effect evaluation Tumor model establishment To establish orthotopic model, K7M2 cells (3 10 6 cells/well) were dispersed in PBS buffer and implanted into right tibia of BALB/c mice

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However, a number of factors, including dose, formulation, and type of study population, affect the bioavailability of tocotrienols and may undermine their putative efficacy in humans (14)